Just a little FYI I got this off the MD webpage
http://www.musculardevelopment.com/content/view/1236/51/
Written by Robbie Durand
Sunday, 11 May 2008
It's the weekend...I time to get hammered! Acute alcohol intoxication has been shown to decrease protein synthesis in a dose dependent manner however gene expression in muscle is unknown.
It's the weekend...I time to get hammered! Acute alcohol intoxication has been shown to decrease protein synthesis in a dose dependent manner however gene expression in muscle is unknown. Researchers examined gene expression in muscle after rats were given an oral dose of alcohol equivalent to acute human alcohol ingestion. Acute alcohol intoxication dramatically up regulated the expression of MuRF1 (The MuRF1 protein was identified as an atrophy-specific factor, whose expression is up-regulated in atrophying muscle.) and, to a lesser extent, atrogin-1 (atrogin-1 is very strongly induced in many catabolic states). The alcohol-induced increase in atrophy genes expression appeared maximal between 4-8 hours after alcohol administration; however, values had returned to basal levels by 24 hours. Moreover, food restriction after alcohol administration was not responsible for this increase. Of note, this increase in atrogin-1 and MuRF1 appeared restricted to predominantly fast-twitch muscles, with no change detected in either the slow-twitch muscles. Don't expect to make gains in muscle if you are drinking and partying..
Vary TC, Frost RA, Lang CH. Acute Alcohol Intoxication
Increases Atrogin-1 and MuRF1 mRNA without Increasing
Proteolysis in Skeletal Muscle. Am J Physiol Regul Integr
Comp Physiol. 2008
MUSCLE BUILDING AND PARTYING
Yes BOSS... we will stop partying and drinking..
thank you for the information
thank you for the information
Strength and healthy
in iron we train and trust
in iron we train and trust
no problem Boss.. I got what you mean in this article
have a good day
have a good day
Strength and healthy
in iron we train and trust
in iron we train and trust
that may be true biggie but it's more fun when you are, haha had to, i do like to party but i keep it to a minimum
"The plates on each side of the bar...they keep us stable, like bookends...this our life, and another chapter is about to unfold"
Good article, Joe. Thanks for posting. Not a problem for me - I never drink alcohol anyway!
Ken
Just a sinner saved by grace
Just a sinner saved by grace
something i need not be worried about...grins...i dont drink..people shouldn't
Trust unto GOD and HE shall lead thee aright
Thanks for this article joe. It's funny seeing all these frat boys at the gym working out, but there talking about how drunk there going to get over the weekend
bulking to 260
I'm with you Ken I stop partying and drinking about 12 years ago.Got all that in when I was young and in the military etc..lol.Great post Joe,thanks for the info always good to learn new things when it comes to your health and fitness etc..Pay attention sandywu the man can teach you something.
Recognize that life is in constant motion and every change happens for a reason.When you see boundries as opportunities,the world becomes a limitless place.

